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F-Phenibut HCL

Regular price €24,80

F-Phenibut HCL, Powder

F-Phenibut HCl (4-Fluorophenibut hydrochloride) is a several-fold more potent derivative of the nootropic and anxiolytic GABA derivative, Phenibut.

F-Phenibut HCl (4-Fluorophenibut hydrochloride) is a several-fold more potent derivative of Phenibut. Phenibut is an atypical anxiolytic and nootropic compound structurally similar to the well known inhibitory neurotransmitter GABA, as well as to baclofen (β-(4-chlorophenyl)-GABA) and pregabalin (β-isobutyl-GABA). Phenibut was originally thought to act solely as a selective GABAB receptor agonist, similar to its much more potent relative baclofen, but has more recently been found to additionally act with somewhat higher affinity as an inhibitor of α2δ subunit-containing voltage-gated calcium channels, a mechanism of action shared with gabapentin and pregabalin.

Phenibut is known to have a wider spectrum of effects than baclofen; for example Phenibut has been found to be more effective as a nootropic and neuroprotective compound than baclofen, while baclofen has a more narrowly focused spectrum of effects and anecdotally shows a reduced tendency to induce habituation or tolerance to its effects upon chronic daily administration.


This Material is Sold For Research Use Only. Terms of Sale Apply. Not for Human Consumption, nor Medical, Veterinary, or Household Uses.

Chemical Information

CAS Number: 1858241-03-8
Purity: ≥98%
Molecular Weight: 233.66 g/mol
Melting Point: Unknown
Molecular Formula: C10FH12NO2 •HCl
Synonyms: 4-Amino-3-(4-fluorophenyl)butanoic acid hydrochloride, 4-Amino-3-(4-fluorophenyl)butyric acid, 4-Fluorophenibut hydrochloride, β-(4-fluorophenyl)-γ-aminobutyric acid hydrochloride, CGP-11130, Fluorophenibut HCL, F-Phenibut, Fluoribut, Fenibut
PubChem CID: 103611

Technical Information

Application: F-Phenibut HCl (4-Fluorophenibut hydrochloride) is a several-fold more potent derivative of the nootropic and anxiolytic gamma amino butyric acid derivative, Phenibut; useful as a GABAB and α2δ subunit-containing voltage-gated calcium channel ligand
Appearance: White or off-white crystalline powder
Physical State: Solid
Solubility: Freely soluble in Ethanol, Water.
Storage: Store at room temperature or cooler, in a sealed airtight container, protected from heat, light and humidity.
Stability: Stable for at least two years when stored as above.

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